Physiological Oxygen in vitro, without the complexity

Recreate in vitro physiological and pathological oxygen conditions.

Enjoy the simplicity of the ready-to-use OxygenControl plate:
no special incubator or hoods needed.

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OxygenControl Plates - Bring Hypoxia to any cell culture

Run multiple physiological oxygen conditions on a single Multi-well plate.

A ready-to-use plate with multiple Oxygen conditions in standard multi-well formats. Test a range of oxygen concentrations simultaneously, a feat never achieved with Hypoxia Chambers, incubators, or specialized equipment.

- Available in standard formats: 6, 12, 24, 48, and 96 wells.

- Flat-bottom, polystyrene plates with lid, coated with InSimili proprietary OxygenControl technology.

- Select between multiple Oxygen levels: 0-3%, 4-6%, 8-10%, 20% (control), or request a custom range.

- Determine the optimal Oxygen concentration for your 2D and 3D cell cultures, or create a dose-response curve across multiple levels.

- Reach stable oxygen concentration within minutes.

- The ready-to-use format can be easily and reliably integrated into your current workflow, saving time and costs.

Oxygen Levels

All available Formats

How OxygenControl Works

The plate is coated with InSimili’s proprietary material, which acts as localized oxygen modulators directly at the cell interface.

Once in contact with standard cell culture media, the coating autonomously regulates dissolved oxygen to the pre-set level – no gas lines, no chambers, no external equipment needed.

Oxygen stabilizes within minutes and is maintained consistently for up to 4days, giving you a reproducible and physiologically relevant microenvironment throughout your experiment.

Technical Specifications

Plate Material Cell-culture grade Polystyrene
Format Multiwell formats: 96, 24, 12, and 6-wells. Petridish format: from 3.5 to 20 cm
Well type Clear. Flat-bottom and U-bottom
Sterility Sterile and ready-to-use
Oxygen Stability Up to 4 days (media-dependent)
Custom formats Available on request
Compatible Media DMEM, RPMI, F-12
Compatible Coatings Laminin, Matrigel, Poly-D-Lysine
Biocompatibility Coating does not chemically interact with cells

Applications

Relevant research areas
Oncology · Immuno-Oncology · Stem Cells · Cardiovascular Disease · Metabolic Analysis

Supported assays
Western Blot · qPCR · Bright field microscopy · Fluorescence microscopy · Confocal microscopy · High-Content imaging · ELISA assays · Immuno-Histochemical staining · HIF pathway evaluation · Hypoxic dose-response assays

Contact us

Get in touch with us to explore what OxygenControl can do for your research. Our scientists will walk you through the science and find the right solution for your studies.